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MPharm Thanet Pitakbut

MPharm Thanet Pitakbut Foto von MPharm Thanet Pitakbut

(+49)231 755-5144


TU Dortmund
FK Bio- und Chemieingenieurwesen
LS Technische Biochemie
Emil-Figge-Str. 66
44227 Dortmund

Raum CT G1 6.27

Field or research

Virtually all plants are inhabited by diverse bacteria and fungi known as endophytes (EMO). These are known to contribute to plant physiology and ecology. Despite this statement, endophyte impact on plants is only documented as single EMO effect without consideration of a systems biology or ecosystems approach to understand the complex network of secondary metabolism in plants and shared endophytes. For a comprehensive understanding of symbiotic beneficial relations, ecological consequences for plant defense and plant fitness, systematic research on genetic and molecular biology level is needed to work out first concepts and strategies of microorganisms for adapting in a hostile plant environment. Plant defense is based also on secondary natural products, which are a potent defense line against insects, invading microorganisms including viruses but also animals as predators. Today it is unclear how endophytes contribute to secondary plant metabolism, if they provide precursors or arm plant metabolites to make them more potent in case of plant pathogen attack. This concept of sharing biosynthesis for mutual benefit is new and will provide exciting opportunities to understand better plant ecology and opens new insight views for gene and drug discovery.